Evolutionary selection across the nuclear hormone receptor superfamily with a focus on the NR1I subfamily (vitamin D, pregnane X, and constitutive androstane receptors)

BACKGROUND: The nuclear hormone receptor (NR) superfamily complement in humans is composed of 48 genes with diverse roles in metabolic homeostasis, development, and detoxification. In general, NRs are strongly conserved between vertebrate species, and few examples of molecular adaptation (positive s...

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Hauptverfasser: Krasowski, Matthew D, Yasuda, Kazuto, Hagey, Lee R, Schuetz, Erin G
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2005
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1262763/
https://ncbi.nlm.nih.gov/pubmed/16197547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-1336-3-2
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