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Simian Virus 5 V Protein Acts as an Adaptor, Linking DDB1 to STAT2, To Facilitate the Ubiquitination of STAT1

The V protein of simian virus 5 (SV5) facilitates the ubiquitination and subsequent proteasome-mediated degradation of STAT1. Here we show, by visualizing direct protein-protein interactions and by using the yeast two-hybrid system, that while the SV5 V protein fails to bind to STAT1 directly, it bi...

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Main Authors: Precious, B., Childs, K., Fitzpatrick-Swallow, V., Goodbourn, S., Randall, R. E.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2005
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1262611/
https://ncbi.nlm.nih.gov/pubmed/16227264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.21.13434-13441.2005
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