The p127 Subunit (DDB1) of the UV-DNA Damage Repair Binding Protein Is Essential for the Targeted Degradation of STAT1 by the V Protein of the Paramyxovirus Simian Virus 5

The V protein of simian virus 5 (SV5) blocks interferon signaling by targeting STAT1 for proteasome-mediated degradation. Here we present three main pieces of evidence which demonstrate that the p127 subunit (DDB1) of the UV damage-specific DNA binding protein (DDB) plays a central role in this degr...

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Hlavní autoři: Andrejeva, J., Poole, E., Young, D. F., Goodbourn, S., Randall, R. E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2002
Témata:
Virus-Cell Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC136798/
https://ncbi.nlm.nih.gov/pubmed/12388698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.22.11379-11386.2002
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