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Functional expression of NF1 tumor suppressor protein: association with keratin intermediate filaments during the early development of human epidermis

BACKGROUND: NF1 refers to type 1 neurofibromatosis syndrome, which has been linked with mutations of the large NF1 gene. NF1 tumor suppressor protein, neurofibromin, has been shown to regulate ras: the NF1 protein contains a GTPase activating protein (GAP) related domain which functions as p21rasGAP...

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Detalhes bibliográficos
Main Authors: Malminen, Maria, Peltonen, Sirkku, Koivunen, Jussi, Peltonen, Juha
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC126231/
https://ncbi.nlm.nih.gov/pubmed/12199909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-5945-2-10
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