Functional expression of NF1 tumor suppressor protein: association with keratin intermediate filaments during the early development of human epidermis

BACKGROUND: NF1 refers to type 1 neurofibromatosis syndrome, which has been linked with mutations of the large NF1 gene. NF1 tumor suppressor protein, neurofibromin, has been shown to regulate ras: the NF1 protein contains a GTPase activating protein (GAP) related domain which functions as p21rasGAP...

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Publié dans:	BMC Dermatol
Auteurs principaux:	Malminen, Maria, Peltonen, Sirkku, Koivunen, Jussi, Peltonen, Juha
Format:	Artigo
Langue:	Inglês
Publié:	BMC 2002
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC126231/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12199909/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-5945-2-10
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