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Evidence that the deep keratin filament systems of the Xenopus embryo act to ensure normal gastrulation.

To study the role of keratin filaments in Xenopus development, fertilized eggs were injected with anti-keratin monoclonal antibodies. The anti-keratin monoclonal antibodies AE1 and AE3 induce abnormal gastrulation; in the most severely affected embryos gastrulation fails completely. In contrast, emb...

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Detalhes bibliográficos
Main Authors: Klymkowsky, M W, Shook, D R, Maynell, L A
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC49995/
https://ncbi.nlm.nih.gov/pubmed/1382297
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