Discrimination between mono- and trimethylated cap structures by two isoforms of Caenorhabditis elegans eIF4E

Primitive eukaryotes like Caenorhabditis elegans produce mRNAs capped with either m(7)GTP or m(3)(2,2,7)GTP. Caenorhabditis elegans also expresses five isoforms of the cap-binding protein eIF4E. Some isoforms (e.g. IFE-3) bind to m(7)GTP–Sepharose exclusively, whereas others (e.g. IFE-5) bind to bot...

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Main Authors: Miyoshi, Hiroshi, Dwyer, Donard S., Keiper, Brett D., Jankowska-Anyszka, Marzena, Darzynkiewicz, Edward, Rhoads, Robert E.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2002
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC126203/
https://ncbi.nlm.nih.gov/pubmed/12198170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf473
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