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Discrimination between mono- and trimethylated cap structures by two isoforms of Caenorhabditis elegans eIF4E

Primitive eukaryotes like Caenorhabditis elegans produce mRNAs capped with either m(7)GTP or m(3)(2,2,7)GTP. Caenorhabditis elegans also expresses five isoforms of the cap-binding protein eIF4E. Some isoforms (e.g. IFE-3) bind to m(7)GTP–Sepharose exclusively, whereas others (e.g. IFE-5) bind to bot...

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Detalhes bibliográficos
Main Authors: Miyoshi, Hiroshi, Dwyer, Donard S., Keiper, Brett D., Jankowska-Anyszka, Marzena, Darzynkiewicz, Edward, Rhoads, Robert E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC126203/
https://ncbi.nlm.nih.gov/pubmed/12198170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf473
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