Discrimination between mono- and trimethylated cap structures by two isoforms of Caenorhabditis elegans eIF4E

Primitive eukaryotes like Caenorhabditis elegans produce mRNAs capped with either m(7)GTP or m(3)(2,2,7)GTP. Caenorhabditis elegans also expresses five isoforms of the cap-binding protein eIF4E. Some isoforms (e.g. IFE-3) bind to m(7)GTP–Sepharose exclusively, whereas others (e.g. IFE-5) bind to bot...

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Détails bibliographiques
Auteurs principaux: Miyoshi, Hiroshi, Dwyer, Donard S., Keiper, Brett D., Jankowska-Anyszka, Marzena, Darzynkiewicz, Edward, Rhoads, Robert E.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2002
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC126203/
https://ncbi.nlm.nih.gov/pubmed/12198170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf473
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