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Suppression of the STK15 oncogenic activity requires a transactivation-independent p53 function
Using a transactivation-defective p53 derivative as bait, STK15, a centrosome-associated oncogenic serine/threonine kinase, was isolated as a p53 partner. The p53–STK15 interaction was confirmed further by co-immunoprecipitation and GST pull-down studies. In co-transfection experiments, p53 suppress...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2002
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC126178/ https://ncbi.nlm.nih.gov/pubmed/12198151 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf409 |
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