Diverse recognition of non-PxxP peptide ligands by the SH3 domains from p67(phox), Grb2 and Pex13p

The basic function of the Src homology 3 (SH3) domain is considered to be binding to proline-rich sequences containing a PxxP motif. Recently, many SH3 domains, including those from Grb2 and Pex13p, were reported to bind sequences lacking a PxxP motif. We report here that the 22 residue peptide lack...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	EMBO J
Hauptverfasser:	Kami, Keiichiro, Takeya, Ryu, Sumimoto, Hideki, Kohda, Daisuke
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Publishing Group 2002
Schlagworte:	Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC126167/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12169629/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf428
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!