Diverse recognition of non-PxxP peptide ligands by the SH3 domains from p67(phox), Grb2 and Pex13p

The basic function of the Src homology 3 (SH3) domain is considered to be binding to proline-rich sequences containing a PxxP motif. Recently, many SH3 domains, including those from Grb2 and Pex13p, were reported to bind sequences lacking a PxxP motif. We report here that the 22 residue peptide lack...

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Pubblicato in:	EMBO J
Autori principali:	Kami, Keiichiro, Takeya, Ryu, Sumimoto, Hideki, Kohda, Daisuke
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 2002
Soggetti:	Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC126167/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12169629/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf428
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