The exon junction complex is detected on CBP80-bound but not eIF4E-bound mRNA in mammalian cells: dynamics of mRNP remodeling

Newly spliced mRNAs in mammalian cells are characterized by a complex of proteins at exon–exon junctions. This complex recruits Upf3 and Upf2, which function in nonsense-mediated mRNA decay (NMD). Both Upf proteins are detected on mRNA bound by the major nuclear cap-binding proteins CBP80/CBP20 but...

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Publié dans:	EMBO J
Auteurs principaux:	Lejeune, Fabrice, Ishigaki, Yasuhito, Li, Xiaojie, Maquat, Lynne E.
Format:	Artigo
Langue:	Inglês
Publié:	Nature Publishing Group 2002
Sujets:	Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC126094/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12093754/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf345
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