Structure of coronavirus main proteinase reveals combination of a chymotrypsin fold with an extra α-helical domain

The key enzyme in coronavirus polyprotein processing is the viral main proteinase, M(pro), a protein with extremely low sequence similarity to other viral and cellular proteinases. Here, the crystal structure of the 33.1 kDa transmissible gastroenteritis (corona)virus M(pro) is reported. The structu...

ver descrição completa

Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Anand, Kanchan, Palm, Gottfried J., Mesters, Jeroen R., Siddell, Stuart G., Ziebuhr, John, Hilgenfeld, Rolf
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 2002
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC126080/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12093723/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf327
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!