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Three-dimensional structure of the human transglutaminase 3 enzyme: binding of calcium ions changes structure for activation

Transglutaminase (TGase) enzymes catalyze the formation of covalent cross-links between protein-bound glutamines and lysines in a calcium-dependent manner, but the role of Ca(2+) ions remains unclear. The TGase 3 isoform is widely expressed and is important for epithelial barrier formation. It is a...

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Hlavní autoři: Ahvazi, Bijan, Kim, Hee Chul, Kee, Sun-Ho, Nemes, Zoltan, Steinert, Peter M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC125988/
https://ncbi.nlm.nih.gov/pubmed/11980702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.9.2055
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