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Three-dimensional structure of the human transglutaminase 3 enzyme: binding of calcium ions changes structure for activation
Transglutaminase (TGase) enzymes catalyze the formation of covalent cross-links between protein-bound glutamines and lysines in a calcium-dependent manner, but the role of Ca(2+) ions remains unclear. The TGase 3 isoform is widely expressed and is important for epithelial barrier formation. It is a...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2002
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125988/ https://ncbi.nlm.nih.gov/pubmed/11980702 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.9.2055 |
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