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Caspase-6 gene disruption reveals a requirement for lamin A cleavage in apoptotic chromatin condensation
To study the role of caspase-6 during nuclear disassembly, we generated a chicken DT40 cell line in which both alleles of the caspase-6 gene were disrupted. No obvious morphological differences were observed in the apoptotic process in caspase-6- deficient cells compared with the wild type. However,...
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| Huvudupphovsmän: | , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Oxford University Press
2002
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125972/ https://ncbi.nlm.nih.gov/pubmed/11953316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.8.1967 |
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