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Stress-inducible caspase substrate TRB3 promotes nuclear translocation of procaspase-3.

Pseudokinase TRB3 is a stress-inducible nuclear protein, which has recently been shown to be involved in ER stress-induced apoptosis. However, it remains unclear how TRB3 contributes to the process. We recently demonstrated that TRB3 was cleaved by caspase-3 (CASP3) in vitro and also in apoptosis-in...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kouhei Shimizu, Shoukichi Takahama, Yaeta Endo, Tatsuya Sawasaki
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science (PLoS) 2012-01-01
Cyfres:PLoS ONE
Mynediad Ar-lein:http://europepmc.org/articles/PMC3415431?pdf=render
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