Caricamento...

Structure of the RPA trimerization core and its role in the multistep DNA-binding mechanism of RPA

The human single-stranded DNA-binding protein, replication protein A (RPA) binds DNA in at least two different modes: initial [8–10 nucleotides (nt)] and stable (∼30 nt). Switching from 8 to 30 nt mode is associated with a large conformational change. Here we report the 2.8 Å structure of the RPA tr...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Bochkareva, Elena, Korolev, Sergey, Lees-Miller, Susan P., Bochkarev, Alexey
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2002
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC125950/
https://ncbi.nlm.nih.gov/pubmed/11927569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.7.1855
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !