Ligands act as pharmacological chaperones and increase the efficiency of δ opioid receptor maturation

The endoplasmic reticulum (ER) is recognized as an important site for regulating cell surface expression of membrane proteins. We recently reported that only a fraction of newly synthesized δ opioid receptors could leave the ER and reach the cell surface, the rest being degraded by proteasomes. Here...

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Bibliographic Details
Main Authors: Petäjä-Repo, Ulla E., Hogue, Mireille, Bhalla, Suparna, Laperrière, André, Morello, Jean-Pierre, Bouvier, Michel
Format: Artigo
Language:Inglês
Published: Oxford University Press 2002
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC125943/
https://ncbi.nlm.nih.gov/pubmed/11927547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.7.1628
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