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Ligands act as pharmacological chaperones and increase the efficiency of δ opioid receptor maturation
The endoplasmic reticulum (ER) is recognized as an important site for regulating cell surface expression of membrane proteins. We recently reported that only a fraction of newly synthesized δ opioid receptors could leave the ER and reach the cell surface, the rest being degraded by proteasomes. Here...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125943/ https://ncbi.nlm.nih.gov/pubmed/11927547 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.7.1628 |
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