Targeted disruption of NBS1 reveals its roles in mouse development and DNA repair
Nijmegen breakage syndrome (NBS) is an autosomal recessive hereditary disease that shares some common defects with ataxia–telangiectasia. The gene product mutated in NBS, named NBS1, is a component of the Mre11 complex that is involved in DNA strand-break repair. To elucidate the physiological roles...
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| Publicado no: | EMBO J |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125926/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11889050/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/21.6.1447 |
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