The hepatitis C viral NS3 protein is a processive DNA helicase with cofactor enhanced RNA unwinding
The RNA helicase/protease NS3 plays a central role in the RNA replication of hepatitis C virus (HCV), a cytoplasmic RNA virus that represents a major worldwide health problem. NS3 is, therefore, an important drug target in the effort to combat HCV. Most work has focused on the protease, rather than...
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| Publicado no: | EMBO J |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125889/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11867545/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/21.5.1168 |
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