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Structural basis for cooperative DNA binding by two dimers of the multidrug-binding protein QacR

The Staphylococcus aureus multidrug-binding protein QacR represses transcription of the qacA multidrug transporter gene and is induced by multiple structurally dissimilar drugs. QacR is a member of the TetR/CamR family of transcriptional regulators, which share highly homologous N-terminal DNA-bindi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Schumacher, Maria A., Miller, Marshall C., Grkovic, Steve, Brown, Melissa H., Skurray, Ronald A., Brennan, Richard G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC125875/
https://ncbi.nlm.nih.gov/pubmed/11867549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.5.1210
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