A masked NES in INI1/hSNF5 mediates hCRM1-dependent nuclear export: implications for tumorigenesis

INI1 (integrase interactor 1)/hSNF5 is a component of the mammalian SWI/SNF complex and a tumor suppressor mutated in malignant rhabdoid tumors (MRT). We have identified a nuclear export signal (NES) in the highly conserved repeat 2 domain of INI1 that is unmasked upon deletion of a downstream seque...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Craig, Errol, Zhang, Zhi-Kai, Davies, Kelvin P., Kalpana, Ganjam V.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 2002
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125819/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11782423/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/21.1.31
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