A masked NES in INI1/hSNF5 mediates hCRM1-dependent nuclear export: implications for tumorigenesis

INI1 (integrase interactor 1)/hSNF5 is a component of the mammalian SWI/SNF complex and a tumor suppressor mutated in malignant rhabdoid tumors (MRT). We have identified a nuclear export signal (NES) in the highly conserved repeat 2 domain of INI1 that is unmasked upon deletion of a downstream seque...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	EMBO J
Päätekijät:	Craig, Errol, Zhang, Zhi-Kai, Davies, Kelvin P., Kalpana, Ganjam V.
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Nature Publishing Group 2002
Aiheet:	Article
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125819/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11782423/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/21.1.31
Tagit:	Lisää tagi Ei tageja, Lisää ensimmäinen tagi!