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Reduced representation bisulfite sequencing for comparative high-resolution DNA methylation analysis
We describe a large-scale random approach termed reduced representation bisulfite sequencing (RRBS) for analyzing and comparing genomic methylation patterns. BglII restriction fragments were size-selected to 500–600 bp, equipped with adapters, treated with bisulfite, PCR amplified, cloned and sequen...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1258174/ https://ncbi.nlm.nih.gov/pubmed/16224102 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki901 |
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