Nalaganje...
Conformation, protein recognition and repair of DNA interstrand and intrastrand cross-links of Antitumor trans-[PtCl(2)(NH(3))(thiazole)]
Replacement of one ammine in clinically ineffective trans-[PtCl(2)(NH(3))(2)] (transplatin) by a planar N-heterocycle, thiazole, results in significantly enhanced cytotoxicity. Unlike ‘classical’ cisplatin {cis-[PtCl(2)(NH(3))(2)]} or transplatin, modification of DNA by this prototypical cytotoxic t...
Shranjeno v:
| Main Authors: | , , , , , |
|---|---|
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2005
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1258167/ https://ncbi.nlm.nih.gov/pubmed/16237123 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki884 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|