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CREB activation induced by mitochondrial dysfunction is a new signaling pathway that impairs cell proliferation
We characterized a new signaling pathway leading to the activation of cAMP-responsive element-binding protein (CREB) in several cell lines affected by mitochondrial dysfunction. In vitro kinase assays, inhibitors of several kinase pathways and overexpression of a dominant-negative mutant for calcium...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125809/ https://ncbi.nlm.nih.gov/pubmed/11782425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.1.53 |
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