Effects of CREB1 gene silencing on cognitive dysfunction by mediating PKA-CREB signaling pathway in mice with vascular dementia

BACKGROUND: As a form of dementia primarily affecting the elderly, vascular dementia (VD) is characterized by changes in the supply of blood to the brain, resulting in cognitive impairment. The aim of the present study was to explore the effects involved with cyclic adenosine monophosphate (cAMP) re...

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Pubblicato in:Mol Med
Autori principali: Han, Xin-Rui, Wen, Xin, Wang, Yong-Jian, Wang, Shan, Shen, Min, Zhang, Zi-Feng, Fan, Shao-Hua, Shan, Qun, Wang, Liang, Li, Meng-Qiu, Hu, Bin, Sun, Chun-Hui, Wu, Dong-Mei, Lu, Jun, Zheng, Yuan-Lin
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6016877/
https://ncbi.nlm.nih.gov/pubmed/30134805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s10020-018-0020-y
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