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Effects of CREB1 gene silencing on cognitive dysfunction by mediating PKA-CREB signaling pathway in mice with vascular dementia

BACKGROUND: As a form of dementia primarily affecting the elderly, vascular dementia (VD) is characterized by changes in the supply of blood to the brain, resulting in cognitive impairment. The aim of the present study was to explore the effects involved with cyclic adenosine monophosphate (cAMP) re...

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Détails bibliographiques
Publié dans:Mol Med
Auteurs principaux: Han, Xin-Rui, Wen, Xin, Wang, Yong-Jian, Wang, Shan, Shen, Min, Zhang, Zi-Feng, Fan, Shao-Hua, Shan, Qun, Wang, Liang, Li, Meng-Qiu, Hu, Bin, Sun, Chun-Hui, Wu, Dong-Mei, Lu, Jun, Zheng, Yuan-Lin
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6016877/
https://ncbi.nlm.nih.gov/pubmed/30134805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s10020-018-0020-y
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