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Mutations in human DNA polymerase η motif II alter bypass of DNA lesions

Human DNA polymerase η (hPolη) is one of the newly identified Y-family of DNA polymerases. These polymerases synthesize past template lesions that are postulated to block replication fork progression. hPolη accurately bypasses UV-associated cis–syn cyclobutane thymine dimers in vitro and contributes...

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Bibliografski detalji
Glavni autori: Glick, Eitan, Vigna, Kellie L., Loeb, Lawrence A.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2001
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC125802/
https://ncbi.nlm.nih.gov/pubmed/11743006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.24.7303
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