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Mutations in human DNA polymerase η motif II alter bypass of DNA lesions
Human DNA polymerase η (hPolη) is one of the newly identified Y-family of DNA polymerases. These polymerases synthesize past template lesions that are postulated to block replication fork progression. hPolη accurately bypasses UV-associated cis–syn cyclobutane thymine dimers in vitro and contributes...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2001
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125802/ https://ncbi.nlm.nih.gov/pubmed/11743006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.24.7303 |
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