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Subunit interaction maps for the regulatory particle of the 26S proteasome and the COP9 signalosome

The 26S proteasome plays a major role in eukaryotic protein breakdown, especially for ubiquitin-tagged proteins. Substrate specificity is conferred by the regulatory particle (RP), which can dissociate into stable lid and base subcomplexes. To help define the molecular organization of the RP, we tes...

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Détails bibliographiques
Publié dans:EMBO J
Auteurs principaux: Fu, Hongyong, Reis, Noa, Lee, Yenfen, Glickman, Michael H., Vierstra, Richard D.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2001
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125776/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11742986/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.24.7096
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