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Subunit interaction maps for the regulatory particle of the 26S proteasome and the COP9 signalosome

The 26S proteasome plays a major role in eukaryotic protein breakdown, especially for ubiquitin-tagged proteins. Substrate specificity is conferred by the regulatory particle (RP), which can dissociate into stable lid and base subcomplexes. To help define the molecular organization of the RP, we tes...

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Dettagli Bibliografici
Pubblicato in:EMBO J
Autori principali: Fu, Hongyong, Reis, Noa, Lee, Yenfen, Glickman, Michael H., Vierstra, Richard D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2001
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125776/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11742986/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.24.7096
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