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Antibody vs. HIV in a clash of evolutionary titans

HIV has evolved many strategies to avoid neutralizing antibody responses, particularly to conserved regions on the external glycoprotein spikes of the virus. Nevertheless, a small number of antibodies have been evolved by the human immune system to recognize conserved parts of the glycoproteins, and...

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Autors principals: Burton, Dennis R., Stanfield, Robyn L., Wilson, Ian A.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1257708/
https://ncbi.nlm.nih.gov/pubmed/16219699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0505126102
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