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Drosophila ATM and ATR checkpoint kinases control partially redundant pathways for telomere maintenance

In higher eukaryotes, the ataxia telangiectasia mutated (ATM) and ATM and Rad3-related (ATR) checkpoint kinases play distinct, but partially overlapping, roles in DNA damage response. Yet their interrelated function has not been defined for telomere maintenance. We discover in Drosophila that the tw...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bi, Xiaolin, Srikanta, Deepa, Fanti, Laura, Pimpinelli, Sergio, Badugu, RamaKrishna, Kellum, Rebecca, Rong, Yikang S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1257705/
https://ncbi.nlm.nih.gov/pubmed/16203987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504981102
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