Nuclear export of phosphorylated C/EBPβ mediates the inhibition of albumin expression by TNF-α

Decreased albumin expression is a frequent feature of cachexia patients afflicted with chronic diseases, including cancer, and a major contributor to their morbidity. Here we show that tumor necrosis-α (TNF-α) treatment of primary mouse hepatocytes or TNF-α overexpression in a mouse model of cachexi...

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Dades bibliogràfiques

Publicat a:	EMBO J
Autors principals:	Buck, Martina, Zhang, Lian, Halasz, Nicholas A., Hunter, Tony, Chojkier, Mario
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Publishing Group 2001
Matèries:	Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125761/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11726507/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.23.6712
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