Nuclear export of phosphorylated C/EBPβ mediates the inhibition of albumin expression by TNF-α
Decreased albumin expression is a frequent feature of cachexia patients afflicted with chronic diseases, including cancer, and a major contributor to their morbidity. Here we show that tumor necrosis-α (TNF-α) treatment of primary mouse hepatocytes or TNF-α overexpression in a mouse model of cachexi...
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| Veröffentlicht in: | EMBO J |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2001
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| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125761/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11726507/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.23.6712 |
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