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PNPase autocontrols its expression by degrading a double-stranded structure in the pnp mRNA leader

Polynucleotide phosphorylase synthesis is autocontrolled at a post-transcriptional level in an RNase III-dependent mechanism. RNase III cleaves a long stem–loop in the pnp leader, which triggers pnp mRNA instability, resulting in a decrease in the synthesis of polynucleotide phosphorylase. The stagg...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Jarrige, Anne-Charlotte, Mathy, Nathalie, Portier, Claude
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2001
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC125756/
https://ncbi.nlm.nih.gov/pubmed/11726520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.23.6845
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