Destructive effects of murine arthritogenic antibodies to type II collagen on cartilage explants in vitro

Certain monoclonal antibodies (mAbs) to type II collagen (CII) induce arthritis in vivo after passive transfer and have adverse effects on chondrocyte cultures and inhibit self assembly of collagen fibrils in vitro. We have examined whether such mAbs have detrimental effects on pre-existing cartilag...

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Detalhes bibliográficos
Main Authors: Crombie, Duncan E, Turer, Muhammed, Zuasti, Beltzane Biurrun, Wood, Bayden, McNaughton, Don, Nandakumar, Kutty Selva, Holmdahl, Rikard, Van Damme, Marie-Paule, Rowley, Merrill J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1257420/
https://ncbi.nlm.nih.gov/pubmed/16207334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1766
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