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XRCC1 coordinates the initial and late stages of DNA abasic site repair through protein–protein interactions

The major human AP endonuclease APE1 (HAP1, APEX, Ref1) initiates the repair of abasic sites generated either spontaneously, from attack of bases by free radicals, or during the course of the repair of damaged bases. APE1 therefore plays a central role in the base excision repair (BER) pathway. We r...

Бүрэн тодорхойлолт

-д хадгалсан:
Номзүйн дэлгэрэнгүй
-д хэвлэсэн:EMBO J
Үндсэн зохиолчид: Vidal, Antonio E., Boiteux, Serge, Hickson, Ian D., Radicella, J.Pablo
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: Nature Publishing Group 2001
Нөхцлүүд:
Онлайн хандалт:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125722/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11707423/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.22.6530
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