XRCC1 coordinates the initial and late stages of DNA abasic site repair through protein–protein interactions

The major human AP endonuclease APE1 (HAP1, APEX, Ref1) initiates the repair of abasic sites generated either spontaneously, from attack of bases by free radicals, or during the course of the repair of damaged bases. APE1 therefore plays a central role in the base excision repair (BER) pathway. We r...

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Publié dans:	EMBO J
Auteurs principaux:	Vidal, Antonio E., Boiteux, Serge, Hickson, Ian D., Radicella, J.Pablo
Format:	Artigo
Langue:	Inglês
Publié:	Nature Publishing Group 2001
Sujets:	Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125722/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11707423/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.22.6530
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