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Cdc13 prevents telomere uncapping and Rad50-dependent homologous recombination

Cdc13 performs an essential function in telomere end protection in budding yeast. Here, we analyze the consequences on telomere dynamics of cdc13-induced telomeric DNA damage in proliferating cells. Checkpoint-deficient cdc13-1 cells accumulated DNA damage and eventually senesced. However, these tel...

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Dades bibliogràfiques
Publicat a:EMBO J
Autors principals: Grandin, Nathalie, Damon, Christelle, Charbonneau, Michel
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2001
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125707/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11689452/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.21.6127
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