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Cdc13 prevents telomere uncapping and Rad50-dependent homologous recombination

Cdc13 performs an essential function in telomere end protection in budding yeast. Here, we analyze the consequences on telomere dynamics of cdc13-induced telomeric DNA damage in proliferating cells. Checkpoint-deficient cdc13-1 cells accumulated DNA damage and eventually senesced. However, these tel...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Grandin, Nathalie, Damon, Christelle, Charbonneau, Michel
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2001
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC125707/
https://ncbi.nlm.nih.gov/pubmed/11689452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.21.6127
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