Cdc13 prevents telomere uncapping and Rad50-dependent homologous recombination
Cdc13 performs an essential function in telomere end protection in budding yeast. Here, we analyze the consequences on telomere dynamics of cdc13-induced telomeric DNA damage in proliferating cells. Checkpoint-deficient cdc13-1 cells accumulated DNA damage and eventually senesced. However, these tel...
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| Veröffentlicht in: | EMBO J |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2001
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| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125707/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11689452/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.21.6127 |
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