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Cdc13 prevents telomere uncapping and Rad50-dependent homologous recombination
Cdc13 performs an essential function in telomere end protection in budding yeast. Here, we analyze the consequences on telomere dynamics of cdc13-induced telomeric DNA damage in proliferating cells. Checkpoint-deficient cdc13-1 cells accumulated DNA damage and eventually senesced. However, these tel...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2001
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125707/ https://ncbi.nlm.nih.gov/pubmed/11689452 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.21.6127 |
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