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Clue to damage recognition by UvrB: residues in the β-hairpin structure prevent binding to non-damaged DNA

UvrB, the ultimate damage-recognizing component of bacterial nucleotide excision repair, contains a flexible β-hairpin rich in hydrophobic residues. We describe the properties of UvrB mutants in which these residues have been mutated. The results show that Y101 and F108 in the tip of the hairpin are...

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書誌詳細
主要な著者: Moolenaar, Geri F., Höglund, Lotta, Goosen, Nora
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2001
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC125699/
https://ncbi.nlm.nih.gov/pubmed/11689453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.21.6140
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