Clue to damage recognition by UvrB: residues in the β-hairpin structure prevent binding to non-damaged DNA
UvrB, the ultimate damage-recognizing component of bacterial nucleotide excision repair, contains a flexible β-hairpin rich in hydrophobic residues. We describe the properties of UvrB mutants in which these residues have been mutated. The results show that Y101 and F108 in the tip of the hairpin are...
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| Publié dans: | EMBO J |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2001
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125699/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11689453/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.21.6140 |
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