The exon–exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay

We recently reported that spliceosomes alter messenger ribonucleoprotein particle (mRNP) composition by depositing several proteins 20–24 nucleotides upstream of mRNA exon–exon junctions. When assembled in vitro, this so-called ‘exon–exon junction complex’ (EJC) contains at least five proteins: SRm1...

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Publié dans:	EMBO J
Auteurs principaux:	Le Hir, Hervé, Gatfield, David, Izaurralde, Elisa, Moore, Melissa J.
Format:	Artigo
Langue:	Inglês
Publié:	Nature Publishing Group 2001
Sujets:	Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125616/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11532962/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.17.4987
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