Genome-wide identification of alternative splice forms down-regulated by nonsense-mediated mRNA decay in Drosophila.
Alternative mRNA splicing adds a layer of regulation to the expression of thousands of genes in Drosophila melanogaster. Not all alternative splicing results in functional protein; it can also yield mRNA isoforms with premature stop codons that are degraded by the nonsense-mediated mRNA decay (NMD)...
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| Principais autores: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science (PLoS)
2009-06-01
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| Serier: | PLoS Genetics |
| Online adgang: | http://europepmc.org/articles/PMC2689934?pdf=render |
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