Genome-wide identification of alternative splice forms down-regulated by nonsense-mediated mRNA decay in Drosophila.

Alternative mRNA splicing adds a layer of regulation to the expression of thousands of genes in Drosophila melanogaster. Not all alternative splicing results in functional protein; it can also yield mRNA isoforms with premature stop codons that are degraded by the nonsense-mediated mRNA decay (NMD)...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Kasper Daniel Hansen, Liana F Lareau, Marco Blanchette, Richard E Green, Qi Meng, Jan Rehwinkel, Fabian L Gallusser, Elisa Izaurralde, Donald C Rio, Sandrine Dudoit, Steven E Brenner
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Public Library of Science (PLoS) 2009-06-01
Schriftenreihe:	PLoS Genetics
Online-Zugang:	http://europepmc.org/articles/PMC2689934?pdf=render
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