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The exon–exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay

We recently reported that spliceosomes alter messenger ribonucleoprotein particle (mRNP) composition by depositing several proteins 20–24 nucleotides upstream of mRNA exon–exon junctions. When assembled in vitro, this so-called ‘exon–exon junction complex’ (EJC) contains at least five proteins: SRm1...

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Main Authors: Le Hir, Hervé, Gatfield, David, Izaurralde, Elisa, Moore, Melissa J.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2001
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC125616/
https://ncbi.nlm.nih.gov/pubmed/11532962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.17.4987
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